The 2022 Mississippi Valley State Delta Devils football team represented Mississippi Valley State University as a member of the East Division of the Southwestern Athletic Conference (SWAC) during the 2022 NCAA Division I FCS football season. Led by Vincent Dancy in his fifth and final season as head coach, the Delta Devils compiled an overall record of 2–9 and a mark of 2–6 in conference play, tying for fifth place in the SWAC's East Division. Mississippi Valley State played home games at Rice–Totten Stadium in Itta Bena, Mississippi.
Schedule
Games summaries
At Tarleton State
At Austin Peay
Delta State
No. 11 Jackson State
At Florida A&M
Alcorn State
At Alabama State
Bethune–Cookman
Alabama A&M
At Southern
Prairie View A&M
References




